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Frequently Asked Questions

JUVÉDERM® XC

Hyaluronic acid (HA) is a naturally occurring substance found on your skin. As you age, you start to lose HA, which causes the skin to lose structure and volume, contributing to the formation of wrinkles and folds.
There are two different types of wrinkles:
  • Dynamic wrinkles are caused when muscles contract to make facial expressions such as smiles and frowns.
  • Static wrinkles develop because our skin's natural substances (such as collagen and hyaluronic acid), which provide structure and volume, decrease over time.

Please see Important Safety Information, including Boxed Warning, for BOTOX® Cosmetic below, or click here.

BOTOX® Cosmetic and JUVÉDERM® XC are two possible ways to treat moderate to severe facial lines and wrinkles. Both are non-surgical, but they work differently:
  • BOTOX® Cosmetic: Injected beneath the skin’s surface to target the underlying muscle activity which is one of the causes of moderate to severe frown lines between the brows and crow’s feet. BOTOX® Cosmetic temporarily reduce the activity of those muscles.
  • JUVÉDERM® XC: Injected into the skin to temporarily smooth moderate to severe wrinkles such as those around the nose and mouth.*†

Please see Important Safety Information, including Boxed Warning, for BOTOX® Cosmetic below, or click here.

* In the United States, JUVÉDERM® XC is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).
This includes all JUVÉDERM® XC injectable gel formulations.
JUVÉDERM® XC is a non-surgical filler your doctor uses to instantly smooth out the lines along the sides of your nose and mouth. It can provide natural-looking results for up to a year with optimal treatment. JUVÉDERM® XC is made from a modified form of hyaluronic acid (HA), manufactured using proprietary HYLACROSS™ technology.
JUVÉDERM® XC non-surgical filler is approved for injection into the mid to deep dermis (below the outer layer of skin) for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases running from the bottom of your nose to the corners of your mouth, also known as parentheses or smile lines).
Do not use this product if you have severe allergies or a history of severe allergic reactions. You should also not use this product if you have allergies to lidocaine or the proteins used to make hyaluronic acid. Your doctor will determine if JUVÉDERM® XC treatment is right for you.
Tell your doctor if you are pregnant, breastfeeding, or have a history of excessive scarring or pigmentation disorders. You should also discuss any medications that you are currently taking that can prolong bleeding, or therapy used to decrease the body's immune response.

JUVÉDERM® XC is the only Hyaluronic Acid (HA) filler FDA-approved* to last up to one year with optimal treatment, and JUVÉDERM® XC was studied in all skin types. Our unique manufacturing process uses HYLACROSS™ technology to provide a high concentration of cross-linked Hyaluronic Acid.

* In the United States, JUVÉDERM® XC is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds.)
Most subjects acquired optimal correction at initial treatment. Some subjects required up to 2 touch-ups to achieve optimal correction.
This includes all JUVÉDERM® XC injectable gel formulations.
Your doctor injects JUVÉDERM® XC non-surgical filler into the skin using a fine needle to temporarily fill in the treatment area and smooth moderate to severe facial wrinkles such as parentheses (smile) lines and marionette lines.

JUVÉDERM® XC non-surgical filler will help to smooth moderate to severe facial wrinkles around the nose and mouth such as parentheses (smile) lines. Results may last up to one year with optimal treatment.

Ask your doctor what you should expect from your initial treatment and when they would recommend scheduling another appointment.

† Most subjects acquired optimal correction at initial treatment. Some subjects required up to 2 touch-ups to achieve optimal correction.
‡ This includes all JUVÉDERM® injectable gel formulations.

Injections may cause some discomfort during and after the injection. JUVÉDERM® XC is formulated with lidocaine for a more comfortable treatment experience.*1 Your doctor may choose to numb (anesthetize) the treatment area to further minimize discomfort.

* Compared to the non-lidocaine JUVÉDERM® formulation.
1 Weinkle SH et al. J Cosmet Dermatol. 2009.

Please see JUVÉDERM® Ultra XC and JUVÉDERM® Ultra Plus XC Patient Safety Information for more information.

The injection process can be performed during a brief office visit. You'll also need to allow time to consult with your doctor prior to treatment. Touch-up injections as well as repeat injections are usually needed to maintain optimal results. Less gel (about half the amount) is usually needed for repeat injections.
It is recommended that you choose a doctor specifically trained in the administration of JUVÉDERM® XC. Click here to find an experienced doctor near you.
Correction is temporary and may last up to one year with optimal treatment. Therefore, touch-up injections, as well as repeat injections, are usually needed to maintain optimal results. Less material (about half the amount) is usually needed for repeat injections.
Most side effects are mild or moderate in nature, and their duration is short lasting (7 days or less). The most common side effects include, but are not limited to, temporary injections site reaction such as redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. As with all skin injection procedures there is a risk of infection. Click here for complete safety information for JUVÉDERM® XC non-surgical filler.

Yes. In fact, JUVÉDERM® XC non-surgical filler has been studied in all skin types.

JUVÉDERM® XC and JUVÉDERM VOLUMA® XC are different products approved to treat different areas of the face. Talk to your doctor to determine the treatment plan that's right for you.

JUVÉDERM® XC is a non-surgical filler your doctor uses to instantly smooth out moderate to severe lines along the sides of your nose and mouth. Natural-looking results may last up to one year with optimal treatment.

JUVÉDERM VOLUMA® XC is the first injectable gel that is FDA-approved to instantly correct age-related volume loss in the cheek area for people over 21. It adds volume, creating contour and lift for up to two years with optimal treatment.

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Please see Important Safety Information, including Boxed Warning, for BOTOX® Cosmetic below, or click here.

JUVÉDERM® XC, JUVÉDERM® ULTRA XC, AND JUVÉDERM VOLUMA® XC IMPORTANT SAFETY INFORMATION

APPROVED USES
JUVÉDERM® XC injectable gel is for injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.

JUVÉDERM® Ultra XC is for injection into the lips and perioral area for lip augmentation in adults over 21.

JUVÉDERM VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss in adults over 21.

IMPORTANT SAFETY INFORMATION

Are there any reasons why I should not receive any JUVÉDERM® injectable gel formulation?
Do not use these products if you have a history of multiple severe allergies or severe allergic reactions (anaphylaxis), or if you are allergic to lidocaine or the gram-positive bacterial proteins used in these products.

What precautions should my doctor advise me about?
  • Tell your doctor if you are pregnant or breastfeeding. The safety of these products for use during pregnancy or while breastfeeding has not been studied
  • The safety of JUVÉDERM® XC and JUVÉDERM® Ultra XC injectable gels in patients under 18 years, and the safety of JUVÉDERM VOLUMA® XC in patients under 35 years or over 65 years has not been studied
  • The safety and effectiveness of JUVÉDERM® XC for areas other than facial wrinkles and folds, and JUVÉDERM® Ultra XC for areas other than the lips and perioral area for lip augmentation, or facial wrinkles and folds, have not been established in clinical studies
  • The safety and effectiveness of JUVÉDERM VOLUMA® XC in areas other than the cheek area have not been established in clinical studies
  • Tell your doctor if you have a history of excessive scarring (eg, hypertrophic scarring and keloid formations) or pigmentation disorders, as use of these products may result in additional scars or changes in pigmentation
  • Tell your doctor if you are planning other laser treatments or a chemical peel, as there is a possible risk of inflammation at the treatment site if these procedures are performed after treatment
  • Patients who experience skin injury near the site of injection with these products may be at a higher risk for side effects
  • Tell your doctor if you are on immunosuppressive therapy used to decrease the body’s immune response, as use of these products may result in an increased risk of infection
  • Tell your doctor if you are using medications that can prolong bleeding, such as aspirin, ibuprofen, or other blood thinners, as this may result in increased bruising or bleeding at the injection site
  • Minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within the first 24 hours following treatment

What are possible side effects?
The most common side effects include tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration, and itching. With JUVÉDERM® XC and JUVÉDERM® Ultra XC injectable gels, most side effects are mild or moderate and last 14 days or less. For JUVÉDERM VOLUMA® XC, side effects are moderate (uncomfortable) and last 2 to 4 weeks.

One of the risks with using this product is unintentional injection into a blood vessel, and while rare, the complications can be serious and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring.

As with all skin injection procedures, there is a risk of infection.

To report a side effect with JUVÉDERM® XC, JUVÉDERM® Ultra XC, or JUVÉDERM VOLUMA® XC, please call Allergan Product Surveillance at 1-800-624-4261.

For more information, please see Juvederm.com or call Allergan Medical Information at 1-800-433-8871.

Available by prescription only.

BOTOX® Cosmetic (onabotulinumtoxinA) Approved Uses

BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of both moderate to severe crow’s feet lines and frown lines between the eyebrows in adults.

IMPORTANT SAFETY INFORMATION

BOTOX® Cosmetic may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:

  • Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months
  • Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing. If this happens, do not drive a car, operate machinery, or do other dangerous activities

The dose of BOTOX® Cosmetic is not the same as, or comparable to, any other botulinum toxin product.

There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow’s feet lines, or both at the same time.

Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.

Do not take BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.

Tell your doctor about all your muscle or nerve conditions, such as amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease), myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.

Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; weakness of forehead muscles, such as trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to breast-feed (it is not known if BOTOX® Cosmetic passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.

Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin, such as Myobloc®, Dysport®, or Xeomin® in the past (be sure your doctor knows exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.

Other side effects of BOTOX® Cosmetic include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes.

For more information refer to the Medication Guide or talk with your doctor.

To report a side effect, please call Allergan at 1-800-433-8871.

Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.

LATISSE® (bimatoprost ophthalmic solution) 0.03% Important Information

Approved Use

LATISSE® is an FDA-approved treatment to grow eyelashes for people with inadequate or not enough lashes.

Important Safety Information

If you use/used prescription products for eye pressure problems, use LATISSE® under doctor care. May cause brown darkening of the colored part of the eye which is likely permanent. LATISSE® may cause eyelid skin darkening which may be reversible. Only apply at base of upper lashes. DO NOT APPLY to lower lid. Hair may grow outside the treatment area. If you have eye problems/surgery, consult your doctor. Common side effects include itchy and red eyes. If discontinued, lashes gradually return to previous appearance.

To report a side effect, please call Allergan at 1-800-433-8871.

Please see the full LATISSE® Product Information.

Natrelle® Breast Implants Important Information

Who may get breast implants (INDICATIONS)?

Natrelle® Breast Implants are approved for women for the following:

  • Breast augmentation for women at least 22 years old for silicone-filled implants.
  • Breast augmentation for women at least 18 years old for saline-filled implants.
    Breast augmentation includes primary breast augmentation to increase breast size, as well as revision surgery to correct or improve the result of a primary breast augmentation surgery.
  • Breast reconstruction. Breast reconstruction includes primary reconstruction to replace breast tissue that has been removed due to cancer or trauma or that has failed to develop properly due to a severe breast abnormality. Breast reconstruction also includes revision surgery to correct or improve the result of a primary breast reconstruction surgery.

IMPORTANT SAFETY INFORMATION
Who should NOT get breast implants (CONTRAINDICATIONS)?

  • Women with active infection anywhere in their body.
  • Women with existing cancer or pre-cancer of their breast who have not received adequate treatment for those conditions.
  • Women who are currently pregnant or nursing.

What else should I consider (WARNINGS)?

  • Breast implants are not lifetime devices, and not necessarily a one-time surgery.
  • Many of the changes to your breasts following implantation cannot be undone. If you later choose to have your implant(s) removed and not replaced, you may experience unacceptable dimpling, puckering, wrinkling, or other cosmetic changes of the breast, which may be permanent.
  • Breast implants may affect your ability to breastfeed, either by reducing or eliminating milk production.
  • Rupture of a silicone-filled breast implant is most often silent and may not be detected by you or your doctor. You should have an MRI 3 years after your surgery and then every 2 years after that for as long as you have your breast implants to determine if rupture is present. If implant rupture is noted on an MRI, you should have the implant removed, with or without replacement.
  • With breast implants, a routine screening mammography and self-examinations for breast cancer will be more difficult. Ask your doctor to help you distinguish the implant from your breast tissue. Symptoms of a ruptured implant may be hard knots or lumps surrounding the implant or in the armpit, change or loss of size or shape of the breast or implant, pain, tingling, swelling, numbness, burning or hardening. Tell your doctor of these symptoms and remove ruptured implants.
  • Inform any other doctor who treats you of the presence of your implants to minimize the risk of damage to the implants.

What types of conditions require more study (PRECAUTIONS)?
Caution: Notify your doctor if you have any of the following conditions, as the risks of breast implant surgery may be higher:

  • Autoimmune diseases (for example, lupus and scleroderma).
  • A weakened immune system (for example, currently taking drugs that weaken the body’s natural resistance to disease).
  • Planned chemotherapy following breast implant placement.
  • Planned radiation therapy to the breast following breast implant placement.
  • Conditions that interfere with wound healing and blood clotting.
  • Reduced blood supply to breast tissue.
  • Clinical diagnosis of depression or other mental health disorders, including body dysmorphic disorder and eating disorders. Please discuss any history of mental health disorders with your surgeon prior to surgery. Patients with a diagnosis of depression or other mental health disorders should wait for resolution or stabilization of these conditions prior to undergoing breast implantation surgery.

What are some complications with breast implants (COMPLICATIONS)?
Key complications are reoperation, implant removal with or without replacement, implant rupture with silicone-filled implants, implant deflation with saline-filled implants, and severe capsular contracture (severe scar tissue around the implant). Other complications include asymmetry, nipple/breast/skin sensation changes, scarring or wrinkling/rippling. Talk to your doctor about other complications.

Talk to your doctor. For more information see the Patient Brochures at www.allergan.com/labeling/usa.htm or call the Allergan Product Support line at 1-800-433-8871.

To report a problem with Natrelle®, please call Allergan Product Surveillance at 1-800-624-4261.

Natrelle® Breast Implants are available by prescription only.

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